Table 1.
Histologic Classification of Tumors by Demographic and Clinical Characteristics, GOG-210 Trial Participants, 2003–2007, N=3,4341
Type I | Type II | |||||||
---|---|---|---|---|---|---|---|---|
|
|
|
||||||
Grade 1–2 Endometrioid | Grade 3 Endometrioid | Serous | Carcinosarcoma | Clear cell | Mixed epithelial with serous or clear cell components | Other malignant tumors | p-value4 | |
(n=2,244) | (n=354) | (n=321) | (n=141) | (n=77) | (n=42)2 | (n=250)3 | ||
% | % | % | % | % | % | |||
Age, years | <0.001 | |||||||
54 or younger | 28.5 | 19.8 | 6.6 | 10.6 | 9.1 | 9.5 | 18.4 | |
55–59 | 23.0 | 22.9 | 11.2 | 12.1 | 13.0 | 19.0 | 17.2 | |
60–64 | 16.9 | 15.8 | 22.1 | 17.7 | 22.1 | 14.3 | 19.2 | |
65–69 | 12.9 | 13.8 | 19.3 | 22.0 | 19.5 | 23.8 | 15.2 | |
70 or older | 18.7 | 27.7 | 40.8 | 37.6 | 36.4 | 33.3 | 30.0 | |
Median | 59.6 | 61.9 | 67.4 | 66.8 | 66.1 | 66.6 | 63.8 | |
Race | <0.001 | |||||||
White | 91.2 | 89.3 | 77.3 | 71.6 | 81.8 | 92.9 | 86.0 | |
Black | 4.8 | 9.3 | 19.9 | 22.7 | 11.7 | 4.8 | 11.2 | |
Other | 3.2 | 0.8 | 2.2 | 2.8 | 5.2 | 2.4 | 2.4 | |
Unknown | 0.8 | 0.6 | 0.6 | 2.8 | 1.3 | 0.0 | 0.0 | |
Grade | <0.001 | |||||||
1 | 59.2 | 0.0 | 0.0 | 0.7 | 0.0 | 2.4 | 18.8 | |
2 | 40.8 | 0.0 | 0.0 | 0.7 | 0.0 | 2.4 | 3.3 | |
3 | 0.0 | 100.0 | 100.0 | 4.3 | 100.0 | 16.7 | 36.7 | |
Not graded | 0.0 | 0.0 | 0.0 | 94.3 | 0.0 | 78.6 | 40.0 | |
Stage | <0.001 | |||||||
I | 84.3 | 65.5 | 48.9 | 52.5 | 55.8 | 57.1 | 59.2 | |
II | 6.3 | 7.3 | 6.2 | 7.8 | 18.2 | 9.5 | 10.4 | |
III | 8.4 | 20.1 | 30.5 | 28.4 | 20.8 | 21.4 | 23.2 | |
IV | 1.0 | 7.1 | 14.3 | 11.4 | 5.2 | 11.9 | 7.2 |
Five endometrioid cases were not graded
Mixed epithelial include: mixed serous/endometrioid (n=26), mixed clear cell/endometrioid (n=11), mixed serous/clear cell (n=5)
Other malignant tumors include: mixed epithelial not otherwise specified (n=190), undiffferentiated carcinoma (n=20), mucinous adenocarcinoma (n=14), de-differentiated carcinoma (n=12), other carcinoma (n=12), squamous cell carcinoma (n=3), small cell carcinoma (n=2), unknown (n=2), granulosa cell tumor (n=1)
Chi-square p-value