Table 2.
Treatment courses | n (%) |
EBRT then SBRT | 23 (70) |
SBRT then SBRT | 7 (21) |
SBRT then EBRT | 3 (9) |
Median interval between courses (range) | 18 months (6–61) |
Data for first XRT course | |
All patients (n = 33) | |
Median dose all patients (range) | 60 Gy (22.5–80.5 Gy) |
Median number of fractions (range) | 30 (1–37) |
Patients treated initially with SBRT (n = 10, 30%) | |
Median dose (range) | 50 Gy (22.5–60 Gy) |
Median number of fractions (range) | 5 (1–5) |
Fractionation schemes (dose/fraction) | n (%) |
54 Gy in 3 fractions (18 Gy) | 3 (30) |
50 Gy in 5 fractions (10 Gy) | 3 (30) |
40 Gy in 5 fractions (8 Gy) | 1 (10) |
60 Gy in 3 fractions (20 Gy) | 1 (10) |
22.5 Gy in a single fraction | 2 (20) |
Patients treated initially with EBRT (n = 23, 70%) | |
Median dose (range) | 66 Gy (45–80.5 Gy) |
Median number of fractions (range) | 33 (28–37) |
Chemotherapy | 16 (70% of EBRT group) |
Concurrent | 14 (61% of EBRT group |
Sequential | 2 (29% of EBRT group) |
Data for retreatment course* | |
All patients (n = 33) | |
Median dose all patients (range) | 50 Gy (20–70.2 Gy) |
Median number of fractions (range) | 10 (1–35) |
Patients retreated with SBRT (n = 30, 91%) | |
Median dose (range) | 50 Gy (20–54 Gy) |
Median number of fractions (range) | 5 (1–10) |
Fractionation schemes (dose/fraction) | n (% of SBRT patients) |
50 Gy in 10 fractions (5 Gy) | 14 (47) |
40 Gy in 5 fractions (8 Gy) | 3 (10) |
54 Gy in 3 fractions (18 Gy) | 2 (7) |
50 Gy in 5 fractions (10 Gy) | 2 (7) |
36 Gy in 2 fractions (18 Gy) | 2 (7) |
35 Gy in 5 fractions (7 Gy) | 1 (3) |
26 Gy in 2 fractions (13 Gy) | 1 (3) |
20–22.5 Gy in a single fraction | 5 (17) |
Patients retreated with EBRT (n = 3, 9%) | |
Doses for all 3 patients | 66 Gy – 70 Gy – 70.2 Gy |
Number of fractions | 33 – 35 – 26 |
Includes 5 patients treated with >2 courses of XRT.