Table 2.

PACT‐supported translational work

Translational work	Treatment indication or objective
Human embryonic stem cell—derived cardiomyocytes	• Acute and chronic myocardial ischemia
Corneal and oral epithelial stem cells	• Corneal transplantation in patients with corneal limbal stem cell deficiency
Lung‐derived mesenchymal stem cells (MSCs)	• End‐stage emphysema
Bone marrow‐derived MSCs*	• Myocardial infarction• Pulmonary arterial hypertension• Acute lung injury• Lung rejection• 3‐D human lung for transplant• Bronchiolitis obliterans• Stroke• Graft‐versus‐host disease (GVHD)• Vocal fold scarring
Peripheral blood—derived iTregs (expansion ­optimization studies)	• Treatment/prevention of GVHD following hematopoietic stem cell transplantation (HSCT)
Gene modified CD34+ cells	• Treatment of Wiskott‐Aldrich syndrome
Peripheral blood—derived HIV‐1—specific cytotoxic T lymphocytes (CTLs)	• HIV‐1—specific CTL therapy
Fibroblasts	• Wound healing/therapies