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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Stroke. 2014 Mar 18;45(5):1505–1509. doi: 10.1161/STROKEAHA.114.004809

Figure 2. Loss of HEG does not result in CCM formation.

Figure 2

Postnatal deletion Ccm2 in Tie2CreErt2+; Ccm2fl/fl animals results in CCM formation in areas adjacent to the meninges, and in the cerebellum and retina (A). No CCM lesion were identified in the brains of Heg-deficient mice at age 10 months (B) or 17 months (C) age. Arrows indicate CCMs. White scale bars, 1mm; Black scale bars, 100μm.