Figure 4.
(A) Effects of pre- and post-retrieval rimonabant (SR141716; SR) on social play-induced CPP. The experimental protocol is depicted above the graph (Pre-C: pre-conditioning test, CS+: conditioning session with a play-partner, CS-: conditioning session alone). Data represent the mean time (s + SEM) spent in the social compartment (grey and black bars) and the non-social compartment (white bars) during 15 min retrieval- (RETR), test- (TEST) and reinstatement- (REIN) sessions. Vehicle-treated animals (VEH: 2 ml/kg, i.p., n= 19), rimonabant-treated animals (1.0 mg/kg, i.p., treatment pre-retrieval: SRpre: n= 10; treatment post-retrieval: SRpost: n= 8). (B) Time spent scratching during the 15 min test in pre-retrieval rimonabant-treated animals. Independent samples t-test, *p<0.05.