. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: Nat Chem Biol. 2014 Mar 9;10(4):313–318. doi: 10.1038/nchembio.1475

Table 2.

Tests of G4 enrichment parameters show that significance of enrichment of G4 motifs in XPB and XPD peaks is robust with regards to GC content, peak length, and G4 motif specifications.

Region	ChIP	Random Matched GC%		Reduced Peak Size		1–7 nt Loops
Region	ChIP	% Random with G4	ChIP / Random	% Peaks with G4	Binomial p-value	% Peaks with G4	Binomial p-value
TSS±1 kb	XPB	3.37%	18.94	10.88%	7.17e-59	38.45%	0
TSS±1 kb	XPD	3.34%	19.58	11.33%	7.64e-47	39.89%	0
>1 kb from TSS	XPB	2.62%	13.61	6.47%	5.19e-80	18.07%	5.96e-310
>1 kb from TSS	XPD	2.39%	16.00	6.67%	7.79e-55	19.98%	2.00e-243