. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: Nat Chem Biol. 2014 Mar 9;10(4):313–318. doi: 10.1038/nchembio.1475

Table 3.

G4 motifs enriched for XPB and XPD correlate with cancer-associated ontologies. Selected GREAT ontology results for XPB and XPD peaks that contain G4 motifs.

Database	Ontology	Peaks containing G4 motifs
Database	Ontology	XPB	XPD
MSigDB	EGF stimulation	^****	^**
	Fibronectin stimulation	^****	^***
	UVB up-regulation	^****	^****
Pathway Commons	ATR signaling	^**
	RAC1 signaling	^**
	RhoA signaling	^**
	C-MYC	^*	^**
	HIF-1α	^*
	p53	^**

Binomial p-value:

<1e-4;

^**

<1e-8;

^***

<1e-12;

^****

<1e-16.