Table 1.
Study site N=2933 |
HGSC N=1742 |
LGSC N=110 |
MC N=207 |
EC N=484 |
CCC N=390 |
Country (years) | Ascertainment of cases and clinical data | Pathology data and review |
---|---|---|---|---|---|---|---|---|
AOC36 N=208 |
169 | 9 | — | 30 | — | Australia (2002–2006) | Treatment centers throughout Australia; cancer registries serving Queensland, South and West Australia; regular follow-up visits | Pathology reports and diagnostic slides reviewed by panel of gynecologic pathologists |
HAW37, 38 N=108 |
56 | 1 | 11 | 25 | 15 | US (1993–2008) | Hawaii Tumor Registry and medical records | Pathology reports and histological slides reviewed by study pathologist |
MAL39, 40 N=140 |
53 | 9 | 42 | 3 | 33 | Denmark (1994–1999) | Gynecological departments in Copenhagen, Frederiksberg and 7 surrounding counties | Review of pathology reports for all cases and histological slides for 30% by gynecologic pathologist |
MAY+MAC41 N=484 |
331 | 17 | 17 | 86 | 33 | US (2000–2009) | Mayo Clinic medical records and State death certificates | Pathology reports and histologic slides reviewed by Mayo Clinic gynecologic pathologists |
NOT42 N=232 |
127 | 11 | 21 | 48 | 25 | UK (1991–2008) | Hospital records and Trent cancer registry | Pathology reports reviewed by gynecologic pathologist |
POL43 N=81 |
50 | 4 | 8 | 13 | 6 | Poland (2000–2003) | Hospital records and cancer registries serving Warsaw and Lodz | Histological slides reviewed by study pathologist |
RPX44 N=281 |
224 | 12 | 10 | 14 | 21 | US (2000–2011) | Roswell Park Cancer Institute cancer registry and medical records | Pathology reports reviewed by Roswell Park Cancer Institute pathologists |
SEA45 N=179 |
96 | 3 | 13 | 40 | 27 | UK (1998–2008) | East Anglia and West Midlands Cancer Registry | Pathology reports reviewed by central pathologist |
STA46 N=276 |
172 | 19 | 20 | 35 | 30 | US (1997–2001) | Greater Bay Area Cancer Registry | Pathology reports and histological slides reviewed by study pathologist |
TOC47 N=101 |
— | — | 20 | 43 | 38 | Canada (1995–2003) | Ontario Cancer Registry | Pathology reports and histological slides reviewed by study pathologist |
UKO48 N=93 |
49 | 8 | 8 | 12 | 16 | UK (2006–2010) | 10 major Gynecologic Oncology NHS centers in England, Wales and Northern Ireland; cancer registries; NHS Information Centre for Health and Social Care (England and Wales) and Central Services Agency (Northern Ireland) | Central review of pathology reports by gynecologic oncologist |
VAN49, 50 N=750 |
415 | 17 | 37 | 135 | 146 | Canada (1984–2000) | Ovarian Cancer Registry serving British Columbia, and the Cheryl Brown Outcomes unit | Central review of pathology reports and histological slides by University of British Columbia pathologists |
HGSC=high-grade serous carcinoma; LGSC=low-grade serous carcinoma; MC=mucinous carcinoma; EC=endometrioid carcinoma; CCC=clear cell carcinoma.