Table 1.
Participant characteristics (mean ± SD or %) by category of Troponin T (TnT), LITE
| ARIC | ||||||
| TnT Category | 1 | 2 | 3 | 4 | 5* | |
| Range (ng/L) | < 3 | 3 to ≤ 5 | 5 to ≤ 8 | 8 to ≤ 13 | ≥ 13 | |
| N | 3252 | 2463 | 1928 | 1223 | 685 | |
| Age, years | 60.6 ± 5.0 | 62.4 ± 5.5 | 63.6 ± 5.6 | 64.9 ± 5.6 | 65.1 ± 5.7 | |
| Female, % | 78.6 | 61.2 | 45.5 | 34.2 | 24.7 | |
| African American, % | 22.0 | 19.9 | 22.2 | 24.4 | 31.2 | |
| BMI, kg/m2 | 28.0 ± 5.4 | 28.4 ± 5.4 | 28.9 ± 5.5 | 29.3 ± 5.2 | 29.7 ± 5.5 | |
| Diabetes, % | 9.9 | 11.8 | 16.0 | 20.1 | 36.1 | |
| eGFR, ml/min/1.73m2 | 84.6 ± 19.1 | 82.7 ± 19.1 | 79.7 ± 19.2 | 77.1 ± 19.9 | 72.1 ± 21.4 | |
| CRP, mg/L | 4.58 ± 6.10 | 4.15 ± 6.31 | 3.94 ± 5.80 | 3.97 ± 6.18 | 5.50 ± 9.20 | |
| CHS | ||||||
| N | 1463 | 594 | 742 | 687 | 636 | |
| Age, years | 70.7 ± 4.0 | 72.2 ± 4.6 | 73.1 ± 5.0 | 74.6 ± 5.8 | 76.7 ± 6.6 | |
| Female, % | 78.5 | 68.0 | 55.5 | 47.3 | 38.7 | |
| African American, % | 15.5 | 13.5 | 14.8 | 15.0 | 22.0 | |
| BMI, kg/m2 | 26.6 ± 4.5 | 26.1 ± 4.7 | 26.6 ± 4.8 | 26.9 ± 4.5 | 26.4 ± 4.6 | |
| Diabetes, % | 9.6 | 12.1 | 15.5 | 18.1 | 24.5 | |
| eGFR, ml/min/1.73m2 | 70.9 ± 14.8 | 68.6 ± 14.3 | 66.5 ± 16.2 | 63.2 ± 16.1 | 58.1 ± 17.6 | |
| CRP, mg/L | 3.18 ± 5.02 | 3.28 ± 5.18 | 2.80 ± 3.92 | 3.37 ± 5.72 | 4.22 ± 6.72 | |
*
All linear trends in risk factors across the TnT categories are statistically significant at p<0.005, except CRP in ARIC (p = 0.98) and BMI in CHS (p = 0.59).