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. 2014 Apr 22;7:36. doi: 10.1186/1756-8722-7-36

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Copyright © 2014 Gao et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Morphological findings of familial AML-MDS with inherited GATA2 mutations. (A) Peripheral blood smear revealed increased number of blasts, occasional dysplastic neutrophils with hyposegmented nuclei and platelets with abnormal morphology (Wright-Giemsa, ×400). (B) Bone marrow aspirate smears contain occasional blasts with fine chromatin, round nuclei and scant cytoplasm (Wright-Giemsa, ×1000). (C) and (D) The bone marrow core biopsy sections showed a markedly hypercelluar bone marrow with significantly increased numbers of blasts (C: Hematoxylin and eosin, ×200, D: Hematoxylin and eosin, ×600).