The effects of sodium tanshinone IIA sulfonate (STS) on infarct size, area at risk (AAR) (A), heart rate (HR) (B), the first derivative of developed pressure (dp/dtmax) (C), left ventricular developed pressure (LVDP) (D) and coronary flow (CF) (E). The isolated hearts from NS-, STS-, and STS+LY294002-treated rats were subjected to 30 min of global ischemia followed by 2 h of reperfusion. The results are expressed as the mean±SEM. bP<0.05 was considered statistically significant among each group. n=8 animals in each group.