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. 2013 May 19;2:230. doi: 10.1186/2193-1801-2-230

Table 1.

Computational time required by MDR, RF and 2LOmb to analyse small-scaled simulated data sets with different numbers of available SNPs, different numbers of causative SNPs and different ratios of case samples from two affected groups

Number of
 Ratio
 Computational time (sec)
  
causative
 of case
 MDR
 RF
 2LOmb
SNPs samples 20 SNPs 20 SNPs 1,000 SNPs 20 SNPs 1,000 SNPs
2&2
 1:3
 6,505
 2
 539
 5
 24
 
 1:1
 6,434
 2
 529
 6
 23
3&3
 1:3
 6,573
 2
 529
 13
 32
 
 1:1
 6,611
 2
 531
 14
 32
4&4
 1:3
 6,372
 2
 534
 32
 45
 
 1:1
 6,528
 2
 538
 27
 46
2&3
 1:3
 6,637
 2
 529
 12
 32
 
 1:1
 6,644
 3
 527
 10
 30
 
 3:1
 6,776
 2
 528
 10
 28
2&4
 1:3
 6,513
 2
 525
 16
 35
 
 1:1
 6,637
 2
 528
 16
 35
 
 3:1
 6,599
 2
 528
 18
 34
3&4
 1:3
 6,369
 2
 526
 22
 38
 
 1:1
 6,410
 2
 530
 25
 45
  3:1 6,435 2 528 22 38

The simulation is carried out on a computer server. The computer server is equipped with a Xeon 2.66 GHz quad-core processor and 4GB of main memory. A CentOS 5.5 operating system is installed on the computer server. The computational time is collected from the processing of multiple independent data sets for each simulation setting. The displayed time is the maximum time required by each algorithm to analyse one data set.