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Three-locus penetrances that lead to the heritability of 0.01
| |
|
Penetrance of genotype |
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| |
CC
|
Cc
|
cc
|
||||||
| Genotype | BB | Bb | bb | BB | Bb | bb | BB | Bb | bb |
|
AA |
0 |
0 |
16K |
0 |
0 |
0 |
0 |
0 |
0 |
|
Aa |
0 |
0 |
0 |
0 |
4K |
0 |
0 |
0 |
0 |
| aa | 0 | 0 | 0 | 0 | 0 | 0 | 16K | 0 | 0 |
AA, BB and CC denote homozygous wild-type genotypes. Aa, Bb and Cc denote heterozygous genotypes. aa, bb and cc denote homozygous variant genotypes. All allele frequencies are equal (pA = pB = pC = 0.5). K = 1/901.
