Table 8.
|
|
|
Penetrance of genotype |
|
||||||
---|---|---|---|---|---|---|---|---|---|---|
|
|
CC
|
Cc
|
cc
|
||||||
Genotype | DD | Dd | dd | DD | Dd | dd | DD | Dd | dd | |
|
BB |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
AA |
Bb |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
bb |
0 |
0 |
64K |
0 |
0 |
0 |
0 |
0 |
0 |
|
BB |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
Aa |
Bb |
0 |
0 |
0 |
0 |
8K |
0 |
0 |
0 |
0 |
|
bb |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
BB |
0 |
0 |
0 |
0 |
0 |
0 |
64K |
0 |
0 |
aa |
Bb |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
bb | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
AA, BB, CC and DD denote homozygous wild-type genotypes. Aa, Bb, Cc and Dd denote heterozygous genotypes. aa, bb, cc and dd denote homozygous variant genotypes. All allele frequencies are equal (pA = pB = pC = pD = 0.5). K = 1/3501.