Table 1.
Clinical, demographic, and neuropsychological information on the patients and healthy controls when appropriate (mean ± SD and range in parentheses).
CIS (n = 30) | Controls (n = 43) | |
---|---|---|
Gender: | ||
Men | 14 | 25 |
Women | 16 | 18 |
Handedness: | ||
Right | 27 | 37 |
Left | 3 | 6 |
First symptom: | ||
Optic neuritis | 6 | — |
Brainstem-cerebellar | 11 | |
Spinal | 1 | |
Sensorimotor | 6 | |
Polysymptomatic | 6 | |
Age (years) | 31.4 ± 9.6 (15–51) |
33.6 ± 10.2 (16–54) |
Education (years) | 13.6 ± 2.6 (6–18) |
14.4 ± 3.2 (6–19) |
Illness duration (years) | 1.5 ± 1.5 (0–5) |
— |
EDSS | 1.0 ± .5 (0–2) |
— |
WASI Vocabulary (z) | .80 ± 1.0 (−1.5 to 2.5) |
.35 ± 0.9 (−1.5 to 2.1) |
WASI Matrices (z) | −.25 ± .9 (−2.5 to 1.4) |
−.08 ± .8 (−2.2 to 1.6) |
CESD | 13.0 ± 12.7 (1–49) |
— |
STAI-B (Trait Anxiety) | 44.2 ± 10.6 (26–68) |
— |
Fatigue | 29.7 ± 11.2 (10–50) |
— |
EDSS: Expanded Disability Status Scale; CESD: Center for Epidemiological Studies Depression Scale; STAI-A: State-Trait Anxiety Inventory Form Y; Fatigue: Fatigue Severity Scale; WASI: Wechsler Abbreviated Scale of Intelligence. Standard (z) scores on neuropsychological tests.