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Effects of AVE8134, rosiglitazone and fenofibrate on scavenger receptors in cultured human monocytes. (A) Human MonoMac-6 cells were incubated respectively for 18 h. Thereafter mRNA expression was measured for CD36 and MSR1 by realtime-quantitative PCR. (B) Uptake of fluorescent labelled ox-LDL into monocytes. Cells were pre-treated for 24 h with the respective treatments, before fluorescent ox-LDL was added for further 4 h incubation. n=3. Mean±SEM. bP<0.05 vs control treatment.
