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. 2009 Jul 13;30(8):1081–1091. doi: 10.1038/aps.2009.95

Figure 11.

Figure 11

Breviscapine decreased the expression of TNF-α in diabetic rats hearts. Diabetic rats (DM) showed higher expression of TNF-α in heart tissues compared with normal control rats (Control) analyzed by RT-PCR. Treatment with breviscapine reduced the expression of TNF-α in diabetic cardiomyopathy, the reduced expression of TNF-α was more obvious in diabetic rats treated with breviscapine 25 mg·kg−1·d−1 (DM+HDB) than those received 10 mg·kg−1·d−1 breviscapine (DM+LDB), GAPDH was an endogenous control. Each bar represents the mean±SEM. n=8−10 rats for each group. bP<0.05 vs control. eP<0.05 vs DM.