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Dispersed expression and distribution of ERG mRNA, MMP-9 mRNA and protein, and PKCε mRNA and pPKCε protein among the LV, septum, and RV regions were found in ISO medicated rats. These were mitigated by CPU0213 or aminoguanidine (AMI). (A) ERG mRNA; (B) MMP-9 mRNA; (C) MMP-9 protein; (D) PKCε mRNA; (E) pPKCε protein. n=6. Mean±SD. bP<0.05, cP<0.01 vs normal; eP<0.05, fP<0.01 vs ISO. hP<0.05, iP<0.01 vs septum; kP<0.05, lP<0.01 vs RV.
