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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Psychopharmacology (Berl). 2013 Jul 9;230(4):509–524. doi: 10.1007/s00213-013-3178-6

Fig. 1. Nicotine self-administration in perinatal HFD and Chow offspring.

Fig. 1

(A) Mean ± SEM number of nicotine infusions and (B) active and inactive lever responses during the first 23 days of nicotine self-administration (0.015 mg/kg per infusion) under FR-1, FR-2, FR-3 and FR-5 reinforcement schedules. * Represents significant differences between HFD and Chow diet animals with active lever presses (p<0.05). Abbreviations: HFD - high-fat diet.