Figure 2. Overlapping sets of genes determined by two linear models.

Two linear mixed models were used, a published model [13] (see Equation (2)) and a modified version including counts of different blood cell types as potential confounders of gene expression (see Equation (1)). Differential expression was determined based on altered fold changes in at least one of the four previously chosen dose ranges of benzene exposure, with an FDR-adjusted p-value<0.05.