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. 2014 May 1;9(5):e91828. doi: 10.1371/journal.pone.0091828

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© 2014 Thomas et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Hierarchical cluster of the probes in the AML pathway. The probes are clustered based on the distance between the corresponding rows of the matrix, given in Equation (6). The figure is a visual representation of the distance matrix between all the probes/genes in the pathway. The color of the (i,j)^th position of the distance matrix is a measure of how close probes i and j are to each other based on their response across the dose range. The color ranges from white to red. The closer the pair of probes is two each other, the greater the intensity of red at the corresponding position. The dashed black lines correspond to boundaries of clusters of probes as determined by the HOPACH algorithm [47].

Inline graphic — Hierarchical cluster of the probes in the AML pathway. The probes are clustered based on the distance between the corresponding rows of the matrix, given in Equation (6). The figure is a visual representation of the distance matrix between all the probes/genes in the pathway. The color of the (i,j)^th position of the distance matrix is a measure of how close probes i and j are to each other based on their response across the dose range. The color ranges from white to red. The closer the pair of probes is two each other, the greater the intensity of red at the corresponding position. The dashed black lines correspond to boundaries of clusters of probes as determined by the HOPACH algorithm [47].