Table 3. Performance of PURE-LAMP based on different sputum and different sputum combination.
| No. of TB test | Sensitivity | Specificity (No-tuberculosis) | PPV | NPV | Diagnostic accuracy |
| 3 samples (spot, morning, and night sputum) | |||||
| Correct–no./total no.(%) | 333/375(88.80) | 924/954(96.86) | 333/363(91.74) | 924/966(95.65) | 1257/1329(94.58) |
| 95% CI | (85.21–91.61) | (95.55–97.79) | (88.45–94.15) | (94.18–96.77) | 93.23–95.68 |
| 2 samples | |||||
| Spot and night sputum | |||||
| Correct–no./total no.(%) | 310/375(82.67) | 929/954(97.38) | 310/335(92.54) | 929/994(93.46) | 1239/1329(93.23) |
| 95% CI | (78.51–86.16) | (96.16–98.22) | (89.22–94.89) | (91.75–94.84) | (91.75–94.46) |
| Spot and morning sputum | |||||
| Correct–no./total no.(%) | 309/375(82.40) | 928/954(97.27) | 309/335(92.24) | 928/994(93.36) | 1237/1329(93.08) |
| 95% CI | (78.22–85.92) | (96.04–98.13) | (88.87–94.65) | (91.64–94.75) | (91.58–94.32) |
| Night and morning sputum | |||||
| Correct–no./total no.(%) | 314/375(83.73) | 931/954(97.59) | 314/337(93.18) | 931/992(93.85) | 1245/1329(93.68) |
| 95% CI | (79.66–87.12) | (96.41–98.39) | (89.97–95.41) | (92.18–95.18) | (92.24–94.87) |
| 1 sample | |||||
| Spot sputum | |||||
| Correct–no./total no.(%) | 265/375(70.67) | 938/954(98.32) | 265/281(94.31) | 938/1048(89.50) | 1203/1329(90.52) |
| 95% CI | (65.87–75.05) | (97.29–98.97) | (90.95–96.47) | (87.50–91.22) | (88.83–91.98) |
| Night sputum | |||||
| Correct–no./total no.(%) | 267/375(71.20) | 938/954(98.32) | 267/283(94.35) | 938/1046(89.67) | 1205/1329(90.67) |
| 95% CI | (66.42–75.55) | (97.29–98.97) | (91.01–96.49) | (87.68–91.38) | (88.99–92.12) |
| Morning sputum | |||||
| Correct-no./total no.(%) | 261/375(69.60) | 935/954(98.01) | 261/280(93.21) | 935/1049(89.13) | 1196/1329(89.99) |
| 95% CI | (64.76–74.04) | (96.91–98.72) | (89.65–95.61) | (87.10–90.88) | (88.26–91.49) |