Table 1.
Comparisons of biologic parameters during 25 patients’ sickle-cell disease vaso-occlusive crises (VOC) and at steady state (ST)
| Parameter | VOC | ST | P value |
|---|---|---|---|
| Hemoglobin (g/dL) |
8.3 ± 1.3 |
8.8 ± 1.2 |
0.01 |
| White blood-cell count (106/L) |
12216 ± 4599 |
9832 ± 3359 |
0.009 |
| Lactate dehydrogenase (IU/L) |
434.8 ± 181.5 |
392.5 ± 213.1 |
0.16 |
| Creatinine (μmol/L) |
60.3 ± 16.8 |
57.5 ± 16.1 |
0.24 |
| Urea (mmol/L) |
2.2 ± 1.1 |
2.9 ± 1.1 |
0.01 |
| Albuminuria (mg/L) |
71.1 ± 259.4 |
139.4 ± 347.0 |
0.14 |
| Albuminuria/creatinuria (mg/mmol) |
14.6 ± 47.5 |
18.4 ± 46.9 |
0.38 |
| Urine NGAL (ng/mL) |
76.7 ± 76.7 |
28.7 ± 25.7 |
0.007 |
| NGAL/creatinuria (mg/mmol) |
17.1 ± 20.7 |
3.9 ± 3.6 |
0.004 |
| C-Reactive protein (mg/L) | 54.9 ± 60.5 | 9.1 ± 7.2 | 0.003 |
Values are means ± standard deviation.