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. 2014 May 1;9(5):e96408. doi: 10.1371/journal.pone.0096408

Figure 6. Serum MMP-2/MMP-9 activity pre- and post-drug delivery.

Figure 6

Dogs were first randomized into 3 treatment groups, and serum was obtained prior to administration of saline, DMSO, or GM6001 (panel A). There were no differences in serum MMP-2/MMP-9 activity among treatment groups at the time of admission (panel A); however, at day 3, there was a significant (P = 0.0482) difference in serum activity between GM6001-treated dogs and the other treatment groups (panel B). See Figure 5 for a description of box-and-whisker plots. Groups marked with different letters differ significantly (P<0.05).