Table 1. Baseline characteristics did not differ significantly among treatment groups.
| A. Continuous variables: Medians (range); P values from Kruskal-Wallis testing | |||||||||
| Variable | Saline Controls | DMSO | Drug+DMSO | P value | |||||
| (N = 38) | (N = 33) | (N = 33) | |||||||
| Age (years) | 5 (2 to 13) | 5 (3 to 13) | 5 (2 to 14) | 0.9833 | |||||
| Duration of signs prior to admission (hours) | 24 (1 to 48) | 18 (4 to 36) | 12 (2 to 48) | 0.2246 | |||||
| MFS* | 2 (0 to 3) | 2 (0 to 3) | 2 (0 to 3) | 0.7409 | |||||
| TSCIS# | 4 (0 to 10) | 4 (0 to 11) | 4 (0 to 10) | 0.5907 | |||||
| B. Categorical variables: P values from chi-squared testing | |||||||||
| Variable | DMSO | Drug+DMSO | P value | ||||||
| (N = 38) | (N = 37) | (N = 33) | |||||||
| Sex | Female | 61% (23/38) | 53% (19/36) | 39% (13/33) | 0.3039 | ||||
| Male | 39% (15/38) | 47% (17/36) | 61% (20/33) | ||||||
| Neutered | No | 16% (6/38) | 22% (8/36) | 18% (6/33) | 0.9078 | ||||
| Yes | 84% (32/38) | 78% (28/36) | 82% (27/33) | ||||||
| Breed | Dachshund | 71% (27/35) | 61% (22/36) | 85% (28/33) | 0.1560 | ||||
| Other | 29% (8/35) | 39% (14/36) | 15% (5/33) | ||||||
| Chondrodystrophoid | Yes | 89% (34/38) | 86% (31/36) | 88% (29/33) | 0.9628 | ||||
| Other | 11% (4/38) | 14% (5/36) | 12% (4/33) | ||||||
| Level of Spinal Cord Injury | T12-T13 | 34% (13/38) | 36% (13/36) | 24% (8/33) | 0.6986 | ||||
| T13-L1 | 29% (11/38) | 25% (9/36) | 33% (11/33) | 0.8705 | |||||
| L1-L2, L2-L3, or L3-L4 | 29% (11/38) | 33% (12/36) | 24% (8/33) | 0.8390 | |||||
| T2-Weighted Hyperintensity (only available for 76 dogs) | Absent | 62% (18/29) | 76% (22/29) | 50% (9/18) | 0.3225 | ||||
| Present | 38% (11/29) | 24% (7/29) | 50% (9/18) | ||||||
Panel A summarizes continuous variables using medians (ranges) by group, with P values from Kruskal-Wallis tests; panel B describes categorical variables using proportions by group with P values from chi-squared testing. * MFS = Modified Frankel Score; # TSCIS = Texas Spinal Cord Injury Score.