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. 2014 May 1;9(5):e96192. doi: 10.1371/journal.pone.0096192

Figure 4. Transcriptional activity of wild-type and mutant HOXD13 proteins at the human EPH7A promoter.

Figure 4

The R31Q (p.R306Q), R31G (p.R306G) and I47L (p.I322L) mutants show a significantly diminished stimulation compared with the wild-type control at approximately 62%, 60% and 58% of the wild-type HOXD13, respectively. Bars represent firefly/Renilla luciferase ratios for the different constructs.