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. 2014 May 1;9(5):e96609. doi: 10.1371/journal.pone.0096609

Figure 2. Characterization of humoral immune response elicited by DNA vaccination.

Figure 2

Sera from groups of mice immunized intramuscularly with DNA vaccines with and without the CpG ODN 1826 were analyzed for the presence of antigen-specific antibodies by ELISA. A) Comparison of anti-PE specific antibodies. B) Comparison of anti-PcrV specific antibodies. Bar, mean and SEM from 3 independent experiments, each using at least three mice per group (n = 15 for one vaccine group); # P<0.05 between the indicated pairs, NS no significance in statistics, * P<0.05 versus PBS vaccinated group.