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. 2014 May 1;9(5):e96609. doi: 10.1371/journal.pone.0096609

Figure 3. Proliferation of splenic cells from mice immunized with DNA vaccines.

Figure 3

One week after the last administration, splenic cells of mice were collected and cultured respectively with A) Pseudomonas Exotoxin A and B) recombinant PcrV for 72 hours, then the stimulation index (SI) of splenic cells within different groups was calculated to determine the proliferation activity. Bar, mean and SD from 2–4 independent experiments, each using at least three mice per group (n = 15 for one vaccine group); # P<0.05 between the indicated pairs, *P<0.05 versus PBS vaccinated group.