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. 2014 May 1;9(5):e94864. doi: 10.1371/journal.pone.0094864

Figure 2. Frequency of nucleotide mutations and amino acid substitutions within HBV RT domain (n = 64).

Figure 2

The values are presented as the percent nucleotide mutations (upper panel) or amino acid substitution (lower panel) compared to the wild-type genotype C hepatitis B virus (HBV) DNA sequence. The locations of the domains (A–F) are shown at the top of the figure. The pre-S/S-overlapping region in the polymerase gene is identified by grey areas. Abbreviation: HBV, hepatitis B virus; RT, reverse transcriptase.