Table 2. COMT enzyme activity in ACI rat mammary and liver tissues.
Treatment and Tissue | COMT Activity (nmol/mg protein/min) |
Fold Change |
---|---|---|
Control-mammary | 0.095 ± 0.009 | 1 |
E2-treated mammary | 0.22 ± 0.029 | 2.31* |
Quercetin-treated mammary | 0.043 ± 0.015 | 0.46* |
Quercetin + E2-treated mammary | 0.038 ± 0.015 | 0.39* |
Control-liver | 5.48 ± 0.751 | 1 |
E2-treated liver | 4.59 ± 0.285 | 0.84 |
Quercetin-treated liver | 3.37 ± 0.176 | 0.61 |
Quercetin + E2-treated liver | 4.36 ± 0.463 | 0.79 |
Activity of the COMT enzyme was measured in mammary and liver tissues from control, E2, quercetin and quercetin + E2-treated rats after 240 days of treatment. Column one lists the treatment each group of animals received and organs in which COMT enzyme activity was quantified. Column two shows the COMT activity as an average of values obtained for at least 4 different animals ± SEM. Column three shows the fold change in COMT enzyme activity compared to the respective control tissue.
Indicates a p value <0.05 compared to respective control tissue.