Table 1.
Effect of ABG on liver weight and markers for liver damage in carbon tetrachloride-induced liver injury model
| Untreated | CCl4 + vehicle | CCl4 + ABG (100mg/kg) | CCl4 + ABG (200 mg/kg) | |
|---|---|---|---|---|
|
| ||||
| Liver weight (g) | 8.0 ± 0.7* | 10.0 ± 1.0 | 9.6 ± 1.1 | 9.3 ± 0.7 |
| AST (IU/L) | 278.2 ± 543.5* | 8,530.0 ± 3,239.0 | 6,296.0 ± 2,184.2 | 5,904.0 ± 1,681.8* |
| ALT (IU/L) | 93.4 ± 157.7* | 3,288.0 ± 1,093.2 | 2,500.0 ± 1,095.0 | 2,128.0 ± 896.3* |
| ALP (IU/L) | 524.6 ± 115.5* | 1,910.3 ± 295.4 | 1,733.0 ± 321.2 | 1,615.5 ± 259.3 |
| ALB (g/dl) | 2.3 ± 0.1 | 2.3 ± 0.1 | 2.3 ± 0.2 | 2.2 ± 0.1 |
Each row shows the mean ± S.D. of ten determinations. Statistical significant was analyzed by one-way ANOVA and Dunnett’s t-test (* p < 0.05 vs. vehicle).