Table 3.
Effect of ABG on body weight, adipose tissue weight and plasma lipid profile in HFD-induced obesity model
| CD | HFD + vehicle | HFD + ABG (100 mg/kg) | HFD + ABG (200 mg/kg) | |
|---|---|---|---|---|
|
| ||||
| Body weight (g) | ||||
| Initial | 26.5 ± 1.4* | 35.1 ± 2.5 | 34.1 ± 2.5 | 33.8 ± 2.1 |
| Final | 26.9 ± 1.1* | 39.3 ± 2.6 | 36.6 ± 2.5 | 36.8 ± 3.0 |
| Adipose tissue (mg) | ||||
| Subcutaneous | 357.3 ± 66.3* | 2063.6 ± 253.6 | 1602.5 ± 324.9* | 1569.7 ± 373.0* |
| Epididymal | 428.3 ± 56.2* | 2347.1 ± 337.3 | 2054.3 ± 345.7 | 1896.3 ± 443.2* |
| Mesenteric | 96.4 ± 18.7* | 938.7 ± 98.8 | 848.6 ± 124.2 | 733.2 ± 134.3* |
| Lipid profile (mg/dl) | ||||
| TC | 136.5 ± 9.5* | 199.5 ± 10.3 | 201.6 ± 15.6 | 194.4 ± 9.5 |
| HDL-C | 75.1 ± 5.5* | 98.1 ± 4.4 | 101.5 ± 3.4 | 99.3 ± 5.8 |
| LDL-C | 6.6 ± 1.1 | 6.1 ± 1.1 | 7.5 ± 1.9 | 7.5 ± 1.5 |
| TG | 71.5 ± 8.8 | 80.1 ± 23.3 | 62.1 ± 20.3 | 66.3 ± 23.4 |
Each row shows the mean ± S.D. (n = 8). Statistical significant was analyzed by one-way ANOVA and Dunnett’s t-test (* p < 0.05 vs. vehicle).