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. Author manuscript; available in PMC: 2014 May 2.
Published in final edited form as: Pharmacol Ther. 2008 Jun 13;120(1):1–34. doi: 10.1016/j.pharmthera.2008.05.005

Figure 11. Therapeutic targets on the AGE-RAGE pathway to DN.

Figure 11

The process of AGE damage and RAGE activation offer multiple approaches for preventing neuronal damage, from preventing AGE formation to blocking downstream signaling cascades.