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. Author manuscript; available in PMC: 2014 May 2.
Published in final edited form as: Pharmacol Ther. 2008 Jun 13;120(1):1–34. doi: 10.1016/j.pharmthera.2008.05.005

Table 7.

Approaches to Treatment of Orthostatic Hypotension

Treatment Dose Regimen Possible Side Effects

Support garments

Behavioral advice
 Avoid sudden changes of body posture
 Avoid hot baths and predisposing medications
 Eat frequent small meals
 Take insulin injections lying down

Fludrocortisone 0.1 mg titrated to 0.5 to 2.0 mg/day May predispose to congestive heart failure, hypertension

Sympathomimetics
 Ephedrine 15 – 45 mg, TID Sympathetic symptoms
 Midodrine 2.5 – 10 mg, TID Fewer centrally-mediated side effects
 Clonidine 0.1 – 0.5 mg at bedtime Hypotension

Octreotide 0.1 – 0.5 μg/kg/day Injection site pain, diarrhea