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. 2009 Aug 17;30(9):1316–1322. doi: 10.1038/aps.2009.119

Figure 5.

Figure 5

(A) Cellular protein was isolated from BEL-7402 cells transfected with control or COX-2 siRNA for 48 h and was then subjected to Western blotting analysis for COX-2 protein. COX-2 siRNA inhibits COX-2 protein expression. (B) After BEL-7402 cells were transfected with control or COX-2 siRNA for 48 h the cells were exposed to rosiglitazone (30 μmol/L) in the presence or absence of 5-FU (10 μmol/L). Then, the cell viabilities were determined by MTT assay for 48 h. Data are expressed as the mean±SD of three independent experiments. bP<0.05 vs control group; Con, cells treated with 0.1% DMSO; Con siRNA, non-specific siRNA, as a negative control.