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. 2009 Aug 17;30(9):1253–1261. doi: 10.1038/aps.2009.114

Figure 1.

Figure 1

Kallikrein gene delivery attenuates apoptosis in organs of SHRs. TUNEL-positive (apoptotic) cells were counted in 10 microscopic fields for each tissue section. TUNEL-positive staining of all tissues was significantly reduced in the rAAV-HK-treated SHRs compared with the rAAV-LacZ-treated SHRs (Figure 1A). As seen in the histogram, Kallikrein gene delivery significantly reduced the ratio of TUNEL-positive cells to total tissue cells compared with the control group (n=6, cP<0.01 vs rAAV-LacZ group, Figure 1B).