Table 4. Orthostatic BP changes among genotypes in hypertensive patients.

Orthostatic BP change	Women				Men
ACE2 rs2106809	CC n=972	CT n=1059	TT n=340	P	C n=769	T n=433	P
ΔSBP0, mmHg	−3.9 (−5.6–−2.6)	−2.7 (−5.1–−0.6)	−5.3 (−7.5–−3.9)	0.18	−2.5 (−4.2–0.1)	−4.2 (−6.7–−1.1)	0.30
ΔDBP0, mmHg	2.2 (1.0–3.4)	2.8 (1.2–4.6)	3.2 (1.5–4.3)	0.54	2.8 (1.5–4.7)	0.9 (−1.2–2.9)	0.48
ΔSBP2, mmHg	−2.5 (−4.3–−0.7)	−2.2 (−4.1–−2.0)	−4.3 (−6.8–−2.8)	0.16	−2.4 (−4.2–0.4)	−3.9 (−6.3–−0.5)	0.19
ΔDBP2, mmHg	3.0 (1.8–4.1)	3.3 (1.2–5.0)	3.4 (1.7–5.2)	0.89	3.8 (1.9–5.6)	1.2 (−1.1–3.6)	0.25
ACE2 rs2285666	AA n=700	AG n=1141	GG n=542	A n=680	G n=531
ΔSBP0, mmHg	−2.7 (−4.1–−1.2)	−4.1 (−5.4–−2.7)	−4.6 (−6.3–−3.0)	0.20	−2.6 (−4.2– 0.0)	−4.1 (−5.9–−2.3)	0.24
ΔDBP0, mmHg	2.1 (1.0–3.1)	1.7 (0.8–2.5)	1.5 (0.3–2.5)	0.71	2.7 (1.4–3.9)	1.7 (0.5–3.1)	0.34
ΔSBP2, mmHg	−1.8 (−3.4–−0.2)	−2.8 (−4.2–−1.5)	−2.4 (−4.1–−0.7)	0.67	−1.8 (−3.2–−0.1)	−3.5 (−5.4–−1.6)	0.20
ΔDBP2, mmHg	3.1 (1.9–4.2)	2.9 (2.0–3.7)	2.7 (1.6–3.8)	0.91	4.2 (2.8–5.4)	3.3 (1.7–4.9)	0.43
ACE I/D	II n=874	ID n=1118	DD n=394	II n=412	ID n=571	DD n=232
ΔSBP0, mmHg	−4.0 (−5.2–−2.9)	−4.7(−6.0–−3.5)	−3.1 (−4.5–−1.9)	0.30	−3.4 (−4.2–−1.5)	−1.9 (−3.3–−0.5) -3.7 (−5.1–−1.5)	0.37
ΔDBP0, mmHg	1.0 (0–1.9)	1.02(0– 2.0)	1.22(0.2– 2.1)	0.95	1.3 (0– 2.6)	1.5 (0.1– 3.0) 0.3 (−1.0– 1.6)	0.83
ΔSBP2, mmHg	−2.5 (−3.9–−1.2)	−2.6 (−4.1–−1.3)	−1.4(−2.6–−0.5)	0.45	−2.8 (−3.9–−1.1)	−0.8 (−2.5– 0.9) -2.8 (−4.2– 0.3)	0.24
ΔDBP2, mmHg	2.1 (1.1– 3.1)	2.5 (1.5– 3.2)	2.8(1.8– 3.8)	0.68	2.9 (1.6– 3.9)	3.2 (2.1– 4.5) 2.4 (1.2– 3.6)	0.77

ΔSBP0 indicates systolic blood pressure changes at 0 min after standing; ΔSBP2, systolic blood pressure changes at 2 min after standing; ΔDBP0 or 2, diastolic blood pressure changes at 0 or 2 min after standing.