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. Author manuscript; available in PMC: 2015 Apr 10.
Published in final edited form as: Int J Pharm. 2014 Jan 21;464(0):185–195. doi: 10.1016/j.ijpharm.2014.01.007

Table 1.

Composition and physicochemical parameters of the formulations

Formulation* Lipid Composition Lipid molar ratio Lipid Quantity μmol Magnetite Type Magnetite Amount (mg) Particle Size (nm) PDI Zeta Potential (mV) Entrapment Efficiency (%)
F-1 DPPC: CH 70:30 50 Anionic 5 129.67±4.04 0.15±0.007 −40.4±1.22 4.5±0.5
F-2 Cationic 143±3.22 0.14±0.02 +52.2±2.94 5.5±0.5
F-3 DPPC: CH 60:40 50 Starch coated 5 119.1±2.021 0.34±0.05 −22.5±2.57 66.5±4.5
F-4 70:30 145±2.116 0.23±0.01 −17.3±3.6 62.5±5.5
F-5 80:20 199.8±2.183 0.14±0.01 −6.03±0.94 53±4.1
F-6 DPPC: CH: DSPE-Peg2000 60:40:5 25 Starch coated 5 158.8±2.5 0.09±0.002 −31.4±0.78 59.1±5.05
F-7 70:30:5 163.8±2.35 0.08±0.22 −28.9±0.99 55±3.8
F-8 80:20:5 169.8±1.88 0.11±0.05 −28.6±0.79 51.5±2.9
F-9 DPPC: CH: DSPE-Peg2000 60:40:5 50 Starch coated 5 164.83±4.21 0.12±0.01 −30.3±0.99 91.1±4.1
F-10 70:30:5 170.8±1.93 0.09±0.01 −34.8±0.26 85.5±3.5
F-11 80:20:5 172.9±0.67 0.09±0.01 −33.9±1.29 74.2±4.8
F-12 DPPC: CH: DSPE-Peg2000 60:40:5 75 Starch coated 5 178.9±2.011 0.09±0.01 −28.9±0.79 92.5±4.9
F-13 70:30:5 175.7±3.84 0.09±0.04 −27.8±1.19 86.7±4.6
F-14 80:20:5 180.9±2.58 0.09±0.01 −26.9±1.04 81.5±3.1
F-15 DPPC: CH: DSPE-Peg2000 70:30:5 50 Starch coated 2.5 147.11±3.01 0.96±0.01 −14.9±2.4 88.1±3.8
F-16 10 174.2±1.82 0.12±0.01 −26.2±6.99 76.8±4.9
F-17 20 178.2±1.21 0.09±0.02 −30.03±2.94 54.03±8.03
F-18 DPPC: CH: DSPE-Peg2000 70:30:5 50 - - 130.4±3.98 0.05±0.04 −9.58±1.74 88±4.3
*

F-1 and F-2 were prepared by passive loading but F-3 to F-18 were prepare by active loading