Figure 2.
Selectivity studies for VDR–coactivator interactions inhibition in the presence of PS121912 using FP assay. VDR-LBD (1–10 μM), VDR agonist LG190178 (5 μM), and different coactivator peptides (7 nM) were incubated for 3 h in the presence of different concentrations of compound PS121912.