Table 5.
Ethanol intakes of other adult and peri-adolescent rats under 24-h free-choice access conditions
Conditions | Ethanol Intakes and Blood Ethanol Levels (BELs) | Reference |
---|---|---|
Adult male ALKO Alcohol- Accepting (AA) rats; 10% ethanol vs. water; daily drinking patterns | ~5.3 g/kg/day; periodic binges primarily during the dark phase; peak BEL ~25 mg% | Aalto, 1986 |
Adult male AA rats; 24-h operant; 10% ethanol ad libitum water and food | ~5 g/kg/day | Hyytiä & Sinclair, 1989 |
Adult male AA rats; 10% ethanol vs. water | ~7 g/kg/day to ~7 g/kg/day; testing for alcohol deprivation effect | Sinclair & Li, 1989 |
Adult male Sardinian alcohol- preferring (sP) rats; 10% ethanol vs. water | ~7 g/kg/day to ~7 g/kg/day; 1st hr of re-exposure ~0.7 g/kg/h to ~1.1 g/kg/h; testing for alcohol deprivation effect | Agabio et al., 2000 |
Adult male and female sP rats; 10% ethanol vs. water | ~6.5 g/kg/day; periodic binges primarily during the dark phase; peak BEL ~110 mg% | Colombo et al., 2006 |
Adult male sP rats; 10% or 20% ethanol vs. water; intermittent (MWF) access or continuous (7 days/week) access | ~9 g/kg/day for 20% intermittent access; ~7.5 g/kg/day for 20% continuous access; ~7.5 g/kg/day for 10% intermittent access; ~6.5 g/kg/day for 10% continuous access | Loi et al., 2010 |
Adult female University of Chile B (UChB) alcohol- preferring rats, concurrent 10% and 20% ethanol vs. water | ~7.3 g/kg/day to ~12 g/kg/day; testing for alcohol deprivation effect | Tampier & Quintanilla, 2011 |
Adult female Warsaw alcohol High-Preferring (WHP) rats; 10% ethanol vs. water | 6–8 g/kg/day; ~80% ethanol preference; primarily during dark phase | Dyr & Kostowski, 2008; Zalewska- Kaszubska et al., 2008 |
Adult male and female High ‘Addiction Research Foundation’ (HARF) rats; 10% ethanol vs. water | ~6.5 g/kg/day; ~75% ethanol preference | Lê et al., 2001 |
Adult male and female high ethanol-preferring (HEP) rats; 11% ethanol vs. water | ~6 g/kg/day for females; ~5 g/kg/day for males | Myers et al., 1998 |
Adult Marchigian sP (msP) rats; 10% ethanol vs. water; | ~7 g/kg/day; periodic binges primarily during the dark phase; 80% of ethanol consumed during dark phase, 1st bout within 1 h of dark onset; BELs ~75 mg% after a bout | Ciccocioppo et al., 2006 |
Adult Fawn Hooded (FH/Wjd) rats; 10% ethanol vs. water | ~4 g/kg/day; ~90% ethanol preference | Overstreet et al., 2006 |
Adult male Fawn Hooded rats [Janvier (France)]; 10% ethanol vs. water | ~4.1 g/kg/day considered high preferring; ~3.5 g/kg/day considered low preferring | Femenia et al., 2010 |
Adult male Maudsley Reactive (MR/Har) vs. Maudsley Nonreactive (MNRA/Har) rats; 10% ethanol vs. water | Before adaptation procedures, ~1.5 g/kg/day for MR/Har and ~1.7 g/kg/day for MNRA/Har; after adaptation procedures, ~3.8 g/kg/day for MR/Har and ~3.3 g/kg/day for MNRA/Har; ~60% ethanol preference for MR/Har and ~50% ethanol preference for MNRA/Har | Adams et al., 2002 |
Adult male and female Taste- Aversion-Resistant (TAR) rats; 10% ethanol vs. water | ~5.5 g/kg/day | Orr et al., 2004 |
Adult male Wistar rats; 10% ethanol vs. water | ~2.6 g/kg/day to ~4.4 g/kg/day; testing for alcohol deprivation effect | Sinclair & Li, 1989 |
Young adult male Lewis, Wistar and Wistar-Kyoto rats; 10% ethanol vs. water | ~0.6 g/kg/day for Lewis rats; ~2.6 g/kg/day for Wistar rats; ~0.9 g/kg/day for Wistar-Kyoto rats | Goodwin et al., 2000 |
Adult male Wistar rats; 20% ethanol vs. water; intermittent access (MWF) | Peak at ~6 g/kg/day; ~60 mg% at 45 min into dark phase | Simms et al., 2008 |
Adult male Long-Evans rats; 20% ethanol vs. water; intermittent access (MWF) | Peak at ~5 g/kg/day; ~50% ethanol preference; ~60 mg% at 45 min into dark phase | Simms et al., 2008 |
Adult male Long-Evans rats; 20% ethanol vs. water; intermittent access (MWF) | ~5 g/kg/day | Nielsen et al., 2012 |
Adult male Sprague-Dawley rats; 20% ethanol vs. water; intermittent access (MWF) | Peak at ~4.8 g/kg/day; ~50 mg% BEL at 30 min of access | Bito-Onon et al., 2011 |
Adult male Sprague-Dawley rats; 10% ethanol vs. water; continuous access | Peak at ~1.8 g/kg/day; ~25 mg% BEL at 30 min of access | Bito-Onon et al., 2011 |