TABLE 1.

Bacterial strains used in the study

Strain number	Relevant genotype	Source or Ref.
E. coli
DM4100	Wild type	48
KD1915	DM4100 gyrA (G81C)	49
KD1973	DM4100 gyrA (D82A)	49
KD2372	DM4100 lon−	34
KD3052	KD1915 lon−	This worka
KD3276	DM4100 gyrA (G81D)	This workb
M. smegmatis
mc2155	Wild type (KD1163)	S. Colec
KD1987	mc2155 gyrA (A91V)	19, 50
KD2008	mc2155 gyrA (G89C)	19, 50
KD2012	mc2155 gyrA (G89A)	19, 50

^a Strain prepared by transduction from SG20252 (51) to KD1915 using bacteriophage P1 (29).

^b Strain obtained as a spontaneous mutant selected with PD160788 at 5× MIC (52).

^c Institut Pasteur, Paris, France.