Table 2.
Elevated Biomarker Profiles Post-Crossclamp Release
| Biomarker | Baseline | 1 hour | 6 hours | 24 hours |
|---|---|---|---|---|
| Eotaxin | 29(21–34) | ***84(58–152) | **38(30–49) | 26(19–32) |
| IFN-γ | 61(25–114) | ***284(140–426) | ***216(149–420) | 70(57–118) |
| IL-1a | 378(228–880) | 542(381–782) | **589(453–937) | 502(349–728) |
| IL-1b | 24(14–46) | ***139(62–349) | ***77(49–189) | 37(22–95) |
| IL-6 | 21(10–33) | ***291(148–600) | ***276(197–423) | ***105(86–194) |
| IL-10 | 0.9(0.7–1.1) | ***317(203–546) | ***73(35–147) | ***2.4(1.5–4.3) |
| IL-12p40 | 282(209–392) | ***1110(869–2540) | ***923(695–1410) | 427(305–558) |
| IL-12p70 | 1.9(1.3–3.1) | ***4.1(1.7–72.9) | ***6.4(2.0–21.3) | 2.1(1.6–3.6) |
| IL-15 | 15(11–22) | ***30(19–41) | ***26(19–37) | **20(15–31) |
| IL-8 | 201(101–425) | ***1062(582–2310) | ***959(565–1670) | **470(230–1170) |
| IP-10 | 427(301–569) | ***3340(2430–11100) | ***1935(947–7270) | 350(227–540) |
| MCP-1 | 23(16–32) | ***109(61–193) | ***54(31–97) | 24(19–44) |
| MIP-1a | 115(72–197) | ***390(310–561) | ***267(195–377) | 132(101–196) |
| RANTES | 140(110–181) | ***16950(807–36000) | ***4300(680–3130) | *192(154–279) |
Values are reported as medians with interquartiles ranges, in pg/mL
*
denotes p<0.05;
**
denotes p<0.01;
***
denotes p<0.001