Table 7. P value of tests for population stratification and within-family association between VDR, ESR1 genotypes and obesity phenotypes; BMI, total fat mass, total lean mass and PFM values were adjusted by age. Bold indicates significant P values (P<0.05).
ApaI | FokI | CDX2 | PvuII | XbaI | |
---|---|---|---|---|---|
Tests of population stratification | |||||
BMI | 0.442 | 0.761 | 0.114 | 0.435 | 0.634 |
Fat mass | 0.195 | 0.919 | 0.329 | 0.080 | 0.008 |
Lean mass | 0.960 | 0.375 | 0.379 | 0.397 | 0.456 |
PFM | 0.306 | 0.903 | 0.595 | 0.346 | 0.099 |
Test of total association | |||||
BMI | 0.851 | 0.900 | 0.194 | 0.079 | 0.544 |
Fat mass | 0.165 | 0.069 | 0.001 | 0.009 | 0.900 |
Lean mass | 0.566 | 0.120 | 0.700 | 0.144 | 0.541 |
PFM | 0.082 | 0.030 | 0.003 | 0.047 | 0.807 |
Test of within-family association | |||||
BMI | 0.553 | 0.742 | 0.046 | 0.129 | 0.889 |
Fat mass | 0.059 | 0.193 | 0.004 | 0.002 | 0.049 |
Lean mass | 0.738 | 0.089 | 0.668 | 0.104 | 0.335 |
PFM | 0.067 | 0.120 | 0.020 | 0.039 | 0.158 |
P 1000 permutation of within-family association | |||||
BMI | 0.536 | 0.741 | 0.038 | 0.129 | 0.888 |
Fat mass | 0.110 | 0.290 | 0.012 | 0.013 | 0.127 |
Lean mass | 0.748 | 0.063 | 0.626 | 0.108 | 0.354 |
PFM | 0.049 | 0.087 | 0.009 | 0.023 | 0.153 |