Table 1.
Drug Name | Target(s) | Class |
---|---|---|
Erlotinib | EGFR | Kinase Inhibitor |
Irinotecan | Topoisomerase | Cytotoxic |
AZD0530 | Src, ABL/BCR-ABL, EGFR | Kinase Inhibitor |
AZD6244 | MEK, ERK, MAPK | Kinase Inhibitor |
PD0325901 | MEK, RAF, MAPK | Kinase Inhibitor |
Lapatinib | EGFR, HER2 | Kinase Inhibitor |
17-AAG | HSP90 | Other |
Sorafenib | KIT, PDGFRB, FLT3, FLT4, KDR, RAF1, BRAF | Kinase Inhibitor |
Paclitaxel | Microtubules | Cytotoxic |