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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Pac Symp Biocomput. 2014:125–135.

Table 1.

Nine (9) anticancer inhibitory drugs analyzed in both the CGP and CCLE with primary clinical relevance to ovarian cancer and secondary clinical relevance to breast, and endometrial cancer.

Drug Name Target(s) Class
Erlotinib EGFR Kinase Inhibitor
Irinotecan Topoisomerase Cytotoxic
AZD0530 Src, ABL/BCR-ABL, EGFR Kinase Inhibitor
AZD6244 MEK, ERK, MAPK Kinase Inhibitor
PD0325901 MEK, RAF, MAPK Kinase Inhibitor
Lapatinib EGFR, HER2 Kinase Inhibitor
17-AAG HSP90 Other
Sorafenib KIT, PDGFRB, FLT3, FLT4, KDR, RAF1, BRAF Kinase Inhibitor
Paclitaxel Microtubules Cytotoxic