Fig. 6.—

Distribution and functional classification of genes surrounding the BY-kinases. For each of the five neighboring genes (located upstream and downstream of the BY-kinase), the functional COG category was determined. For each surrounded position, the bar indicates the frequency of each functional gene type (represented here by COG category) among the overall categories of the same position. Bar in the right part represents the COG distribution in all genomes harboring BY-kinases. COG categories are shown in different colors (see the COG color legend) and are associated with the corresponding capital letters: A, RNA processing and modification; B, chromatin structure and dynamics; C, energy production and conversion; D, cell cycle control, cell division, and chromosome partitioning; E, amino acid transport and metabolism; F, nucleotide transport and metabolism; G, carbohydrate transport and metabolism; H, coenzyme transport and metabolism; I, lipid transport and metabolism; J, translation, ribosomal structure, and biogenesis; K, transcription; L, replication, recombination, and repair; M, cell wall/membrane/envelope biogenesis; N, cell motility; O, posttranslational modification; protein turnover, chaperones; P, inorganic ion transport and metabolism; Q, secondary metabolites biosynthesis, transport, and catabolism; R, general function prediction only; S, function unknown; T, signal transduction mechanisms; U, intracellular trafficking, secretion, and vesicular transport; V, defense mechanisms; W, extracellular structures; Y, nuclear structure; Z, cytoskeleton.