Methods	RCT, 2 parallel groups.
	Unit of randomization: individual.
Participants	Dates of data collection: Sept 2003 - April 2004.
	Setting: New Halfa Teaching Hospital, Eastern Sudan.
	Inclusion criteria: planned elective CS (categorized as elective)
	Exclusion criteria: antibiotics within 2 weeks; any visible infection; elevated temperature; allergic to antimicrobials; did not wish to participate
Interventions	Ceftriaxone 1 g IV at anesthetic induction vs no treatment.
Outcomes	Post-operative febrile morbidity (oral temperature ≥ 38 °C twice at least 4 hours apart after first 24 hours
	Post-operative infections (endometritis, wound infection, pelvic abscess, peritonitis, other febrile morbidity (UTI, chest infection, malaria)
	2 perinatal deaths: 1 in each group due to respiratory distress and septicaemia due to imperforate anus
Notes	Developing country.
	Class of antimicrobial: third generation cephalosporin.
	Subgroups:
	elective CS; before cord clamping.
Risk of bias
Item	Authors’ judgement	Description
Adequate sequence generation?	Unclear	“Patients were randomized.”
		No additional details.
Allocation concealment?	Unclear	No information.
Blinding?	No	No blinding.
All outcomes		Not placebo-controlled.
Incomplete outcome data addressed?	Yes	No loss of participants to follow up.
All outcomes		No participant excluded after randomization.
		ITT analysis.
Free of selective reporting?	Unclear	Insufficient information to judge.
Free of other bias?	Unclear	“The 2 groups were well matched at enrolment and there were no statistical differences in the admission variables.”
		There was insufficient other information which to judge.
Overall low risk of bias?	No	Very little information provided, particularly around allocation concealment and it appears not placebo controlled