Methods	‘Randomly divided’ (no details provided); placebo-controlled
Participants	Dates of data collection: December 1981 to August 1982.
	Setting: School of Midwifery, Helsinki, Finland.
	Inclusion criteria: women undergoing CS; elective CSs not included but definition not provided
	Exclusion: antibiotics prior to procedure.
Interventions	Metronidazole 500 mg IV after cutting of cord (N = 109) vs placebo (N = 110)
Outcomes	Wound infection, endometritis, sepsis (temperature > 38.5°C and bacteremia).
Notes	Translated from German.
	Class of antibiotic: nitroimidazole (metronidazole).
	Subgroups:
	type of CS unclear; after cord clamping.
Risk of bias
Item	Authors’ judgement	Description
Adequate sequence generation?	Unclear	“Randomly” divided into 2 groups.
Allocation concealment?	Unclear	No information provided.
Blinding?	Unclear	No details provided.
All outcomes
Incomplete outcome data addressed?	Unclear	No losses or exclusions reported; it appears the analysis was ITT
All outcomes
Free of selective reporting?	Unclear	Insufficient information to judge.
Free of other bias?	Unclear	The groups were comparable in respect of social status, age, parity, duration of pregnancy, primary section/repeat section, axillary temperature before the procedure, localization of skin incision, number of am-nioscopes. There was insufficient other information which to judge
Overall low risk of bias?	Unclear	Overall unclear.