Methods |
Quasi-RCT; 5 parallel groups. |
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Unit of randomization: individual. |
Participants |
Dates of data collection: not reported. |
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Setting: Bursa, Turkey.. |
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Inclusion criteria: women undergoing CS due to acute fetal distress |
Interventions |
Ceftriaxone 1 g (N = 25) vs mezlocillin 2 g (N = 23) vs clindamycin 600 mg and amikacin 500 mg (N = 18) vs sulbactam ampicillin 1 g (N = 25) IV after clamping of the cord vs no treatment (N = 28) |
Outcomes |
Wound infection (redness, tenderness, pain and purulent discharge); UTI (renal angle tenderness, fever, dysuria and pyuria); endometritis (vaginal spotting, purulent discharge with fever and pain) plus positive cultures |
Notes |
Treatment groups combined. |
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All wound infections were positive for coagulase negative staphylococcus |
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Class of antibiotic: third generation cephalosporin vs ureidopenicillin (mezlocillin) vs lincosamide (clindamycin) and aminoglycoside |
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Subgroups: |
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type of CS unclear;
after cord clamping.
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Risk of bias |
Item |
Authors’ judgement |
Description |
Adequate sequence generation? |
No |
“…according to the last digital of the patient’s file number…” |
Allocation concealment? |
No |
“…according to the last digital of the patient’s file number…” |
Blinding? |
Unclear |
Insufficient information provided. |
All outcomes |
|
|
Incomplete outcome data addressed? |
Yes |
No losses or exclusions were reported. It appeared to be an ITT analysis |
All outcomes |
|
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Free of selective reporting? |
Unclear |
Insufficient information to judge. |
Free of other bias? |
Unclear |
The 5 groups were comparable regarding maternal age, ruptured membranes, pelvic examinations, haemoglobin levels. Insufficient information to judge other aspects |
Overall low risk of bias? |
No |
Quasi-RCT means it has high risk of bias. |