Methods |
Randomized into 3 groups (irrigation vs systemic treatment vs no treatment) |
Participants |
Dates of data collection: May 1988 - August 1989. |
|
Setting: Beijing, China. |
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Inclusion criteria: women undergoing both elective (N = 112) and non-elective (N = 105) CS. Only women undergoing an elective CS were randomized to treatment or no treatment and have been included in analysis |
Interventions |
Local irrigation with ampicillin 6 g after delivery of the placenta (N = 39) vs penicillin 5. 6 MU and gentamicin 240,000 U IV immediately after surgery and penicillin 1.6 MU and gentamicin 160,000 U per day IM × 3 days (N = 41) vs no treatment (N = 32). Treatment groups combined |
Outcomes |
Endometritis (presence of any 2 of following: temperature above 37.5° C, uterine tenderness, foul vaginal discharge); abdominal wound infection (cellulitis with small amount ofexudate within 2 months ofoperation); uterine incision infection (associated with late postpartum haemorrhage); fever index |
Notes |
Women undergoing non-elective sections randomized to either treatment group (not included in this review) |
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Class of antibiotic: Penicillin and aminoglycoside or aminopenicillin (ampicillin) |
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Subgroups:
elective CS;
after cord clamping.
|
Risk of bias |
Item |
Authors’ judgement |
Description |
Adequate sequence generation? |
Unclear |
“… randomized…” |
Allocation concealment? |
Unclear |
No information provided. |
Blinding? |
Unclear |
No information provided. |
All outcomes |
|
|
Incomplete outcome data addressed? |
Unclear |
No losses or exclusions were reported. Analysis appears to be ITT |
All outcomes |
|
Free of selective reporting? |
Unclear |
Insufficient information to judge. |
Free of other bias? |
Unclear |
Insufficient information to judge. |
Overall low risk of bias? |
Unclear |
Mostly unclear. |