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. Author manuscript; available in PMC: 2014 May 2.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Jan 20;(1):CD007482. doi: 10.1002/14651858.CD007482.pub2

Comparison 2. Antibiotics versus no antibiotics - subgroup by type of cesarean section.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Maternal febrile morbidity/fever 50 8141 Risk Ratio (M-H, Random, 95% CI) 0.45 [0.40, 0.51]
1.1 Elective cesarean section 15 2433 Risk Ratio (M-H, Random, 95% CI) 0.50 [0.37, 0.68]
1.2 Non-elective cesarean section 15 1951 Risk Ratio (M-H, Random, 95% CI) 0.41 [0.31, 0.52]
1.3 Both elective and non-elective, or undefined cesarean section 24 3757 Risk Ratio (M-H, Random, 95% CI) 0.46 [0.38, 0.55]
2 Maternal wound infection 77 11961 Risk Ratio (M-H, Random, 95% CI) 0.40 [0.33, 0.49]
2.1 Elective cesarean section 15 2433 Risk Ratio (M-H, Random, 95% CI) 0.62 [0.44, 0.88]
2.2 Non-elective cesarean section 20 2458 Risk Ratio (M-H, Random, 95% CI) 0.41 [0.27, 0.63]
2.3 Both elective and non-elective, or undefined cesarean section 46 7070 Risk Ratio (M-H, Random, 95% CI) 0.35 [0.27, 0.46]
3 Maternal endometritis 79 12142 Risk Ratio (M-H, Fixed, 95% CI) 0.38 [0.34, 0.42]
3.1 Elective cesarean section 14 2398 Risk Ratio (M-H, Fixed, 95% CI) 0.39 [0.24, 0.65]
3.2 Non-elective cesarean section 21 2537 Risk Ratio (M-H, Fixed, 95% CI) 0.40 [0.33, 0.47]
3.3 Both elective and non-elective, or undefined cesarean section 48 7207 Risk Ratio (M-H, Fixed, 95% CI) 0.36 [0.32, 0.42]
4 Maternal serious infectious complications 31 5047 Risk Ratio (M-H, Fixed, 95% CI) 0.31 [0.20, 0.48]
4.1 Elective cesarean section 4 545 Risk Ratio (M-H, Fixed, 95% CI) 1.01 [0.04, 24.21]
4.2 Non-elective cesarean section 7 923 Risk Ratio (M-H, Fixed, 95% CI) 0.31 [0.14, 0.69]
4.3 Both elective and non-elective, or undefined cesarean section 22 3579 Risk Ratio (M-H, Fixed, 95% CI) 0.30 [0.17, 0.52]
5 Infant immediate adverse effects 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
5.1 Elective cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
5.2 Non-elective cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
5.3 Both elective and non-elective, or undefined cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
6 Infant oral thrush 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
6.1 Elective cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
6.2 Non-elective cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
6.3 Both elective and non-elective, or undefined cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
7 Maternal urinary tract infection 61 9454 Risk Ratio (M-H, Fixed, 95% CI) 0.56 [0.48, 0.65]
7.1 Elective cesarean section 11 1832 Risk Ratio (M-H, Fixed, 95% CI) 0.90 [0.55, 1.48]
7.2 Non-elective cesarean section 17 2148 Risk Ratio (M-H, Fixed, 95% CI) 0.41 [0.29, 0.57]
7.3 Both elective and non-elective, or undefined cesarean section 37 5474 Risk Ratio (M-H, Fixed, 95% CI) 0.58 [0.48, 0.70]
8 Maternal adverse effects 13 2131 Risk Ratio (M-H, Fixed, 95% CI) 2.43 [1.00, 5.90]
8.1 Elective cesarean section 2 235 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
8.2 Non-elective cesarean section 5 808 Risk Ratio (M-H, Fixed, 95% CI) 2.86 [0.61, 13.31]
8.3 Both elective and non-elective, or undefined cesarean section 6 1088 Risk Ratio (M-H, Fixed, 95% CI) 2.23 [0.75, 6.63]
9 Maternal days in hospital 17 3199 Mean Difference (IV, Random, 95% CI) −0.49 [−0.68, −0.29]
9.1 Elective cesarean section 5 1065 Mean Difference (IV, Random, 95% CI) −0.45 [−0.71, −0.19]
9.2 Non-elective cesarean section 3 586 Mean Difference (IV, Random, 95% CI) −0.45 [−0.77, −0.13]
9.3 Both elective and non-elective, or undefined cesarean section 10 1548 Mean Difference (IV, Random, 95% CI) −0.54 [−0.88, −0.19]
10 Infant days in hospital 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
10.1 Elective cesarean section 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
10.2 Non-elective cesarean section 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
10.3 Both elective and non-elective, or undefined cesarean section 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
11 Infant long-term adverse effects 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
11.1 Elective cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
11.2 Non-elective cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
11.3 Both elective and non-elective, or undefined cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
12 Infant’s immune system development 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
12.1 Elective cesarean section 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
12.2 Non-elective cesarean section 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
12.3 Both elective and non-elective, or undefined cesarean section 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
13 Development of bacterial resistance 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
13.1 Elective cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
13.2 Non-elective cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
13.3 Both elective and non-elective, or undefined cesarean section 0 0 Risk Ratio (M-H, Fixed, 95% CI) Not estimable
14 Costs 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
14.1 Elective cesarean section 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
14.2 Non-elective cesarean section 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
14.3 Both elective and non-elective, or undefined cesarean section 0 0 Mean Difference (IV, Fixed, 95% CI) Not estimable
HHS Vulnerability Disclosure